Telomere Length Correlates with Life Span of Dog Breeds.

Telomeric DNA repeats are lost as normal somatic
cells replicate. When telomeres reach a critically
short length, a DNA damage signal is initiated,
inducing cell senescence. Some studies have indicated
that telomere length correlates with mortality,
suggesting that telomere length contributes to
human life span; however, other studies report no
correlation, and thus the issue remains controversial.
Domestic dogs show parallels in telomere biology to
humans, with similar telomere length, telomere attrition,
and absence of somatic cell telomerase activity.
Using this model, we find that peripheral blood
mononuclear cell (PBMC) telomere length is a strong
predictor of average life span among 15 different
breeds (p < 0.0001), consistent with telomeres playing
a role in life span determination. Dogs lose telomeric
DNA 10-fold faster than humans, which is
similar to the ratio of average life spans between
these species. Breeds with shorter mean telomere
lengths show an increased probability of death
from cardiovascular disease, which was previously
correlated with short telomere length in humans...........
http://www.counteragingwise.com/petsCycloastragenol.html

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Telomere Length Correlates with Life Span of Dog Breeds.

Anti Aging Tips

Someday, if you suddenly find yourself grow forehead wrinkles, crow's feet, you will not be panicked? With the aging process, facing death sniper, you will not feel terrible? Aging, which is the human most afraid words most afraid of humans. Anti-aging, win the anti-aging battle, maintain youthful vigor, that is everyone's dream.

A British study showed that Nobel laureate generally live longer, the average life expectancy up to 77.2 years old. The 2009 Nobel Prize in Physiology or Medicine winner - Elizabeth Blackburn, Carol Greider and Jack Szostak discovered the secret of life, a controlling aging biological clock - Telomeres. They found the human Anti Aging Tips, to help humans open the door to live longer.

Telomeres caps at the ends of chromosome, carries no important human genetic information. Each time human cell division, there will always lose some fragments of the ends of chromosomes, that is parts of telomeres. With the increasing of the number of division, telomere becomes shorter and shorter, when telomere is all lost, the cells no longer replicate updates and go to aging. The body is a cell-based unit, cell aging, the body will start aging. Elizabeth Blackburn also found that the cells have an enzyme called Telomerase, telomerase can extend the damaged telomeres. However, telomerase is dormant in the body, the function is not inspired by, unable to complete the work of extension telomeres, couldn't shoulder the anti-aging mission. After long time unremitting efforts, scientists finally found the telomerase activator Cycloastragenol compound, naturally contained in plants Astragalus. It could effectively activate dormant telomerase , promote telomerase synthesis telomeres, allow cells to restore the ability of replication, enhance cells viability. The cells have much vitality, the body will be more health.

Thanks to the modern medicine advance, so humans discovered anti-aging tips. Thanks to the gift of nature, so humans have anti-aging key--Cycloastragenol Capsule! It can be purchased from www.counteragingwise.com now.

TA-65, Telomerase Activator

TA-65 is a proven telomerase activator.

TA-65 activates the enzyme telomerase which can lengthen telomeres. It was discovered by USA California biotech company Geron, and licensed to T.A Sciences Inc.

T.A Sciences Inc. states that TA-65 is a naturally occurring single molecule found in the ancient Chinese herb Astragalus.

According to the analysis of a USA lab, the active ingredient of TA-65 is 5.4mg of cycloastragenol.

Cycloastragenol CAS No.78574-94-4 was hydrolysis from astragaloside IV. Astragaloside IV was extracted from Astragalus.

It means that cycloastragenol is a telomerase activator.

In the market, there are many cycloastragenol supplement suppliers and CounterAgingWise (www.counteragingwise.com) is one of them.

The Same Molecular,but Better Bioavailability,Better Effectiveness and Lower costs.

How Much Is For TA-65 And Is There Any Alternatives?

TA-65 is charging a ridiculously high price for their brand. To buy 1 bottle of 30 capsules, you need to cost $219.00.

Not sure how long you need to take TA-65 before experiencing any beneficial results. It is usually 4 to 6 months.

If you are healthy adults in 40′s or 50′s, you need to take 1 capsule daily. This means that you need to buy at least 4 bottles and cost $876.00;

If you are healthy adults in 50′s or 60′s, you need to take 2 capsules daily. This means that you need to buy at least 8 bottles and cost $1752.00;

If you are healthy adults over 70 years of age, you need to take 4 capsules daily. This means that you need to buy at least 16 bottles and cost $3504.00; That could be very costly.

From Amazon.com, when you search “CounterAgingWise”,you can find another brand CAW^TM ,their price is only $139.99 for 1 bottle of 30 capsules and free shipping worldwide. The active ingredient is 25mg of cycloastragenol 98%, the dosage is 5 times higher than TA-65 but the price is only 60% of TA-65.

TA-65 Astragalus Supplement

New Anti-aging ingredient——Cycloastragenol

In 2001, a California company Geron isolated a molecule from Chinese herb Astragalus and states that it can activate telomerase.

In 2004, a New York company called TA Sciences Inc. bought the rights from Geron for a secret formulation that they began to market under the name TA-65.

The Supplement Facts on the TA-65 label is Astraglus Root Extract 8mg.

According to the report from US lab AACL, the content of TA-65 actually is 5.44mg of cycloastragenol.

Astragalus is an herb that been used as traditional Chinese medicine for more than 2000 years.

From tons of astragalus, small amount of Cycloastragenol can be gained even if based on advanced extraction technology. That is may explain why the price of TA-65 is expensive.

References:

CounterAging http://www.counteragingwise.com Wise is an company that also can offer Cycloastragenol Capsules but more cheaper price.

The Same Molecular,but Better Bioavailability, Better Effectiveness.